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Francesco Fazio Selected Research

cinnabarinic acid

1/2022Analgesic Activity of Cinnabarinic Acid in Models of Inflammatory and Neuropathic Pain.
12/2020The Trace Kynurenine, Cinnabarinic Acid, Displays Potent Antipsychotic-Like Activity in Mice and Its Levels Are Reduced in the Prefrontal Cortex of Individuals Affected by Schizophrenia.
1/2017Cinnabarinic acid and xanthurenic acid: Two kynurenine metabolites that interact with metabotropic glutamate receptors.
6/2014Cinnabarinic acid, an endogenous agonist of type-4 metabotropic glutamate receptor, suppresses experimental autoimmune encephalomyelitis in mice.

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Francesco Fazio Research Topics

Disease

5Neuroinflammatory Diseases
01/2021 - 08/2010
4Body Weight (Weight, Body)
05/2022 - 01/2004
4Schizophrenia (Dementia Praecox)
12/2020 - 12/2015
3Mental Disorders (Mental Disorder)
10/2022 - 12/2015
3Pain (Aches)
01/2022 - 10/2012
3Inflammation (Inflammations)
01/2021 - 01/2017
3Migraine Disorders (Migraine)
06/2015 - 01/2015
2Neuralgia (Stump Neuralgia)
01/2022 - 10/2012
2Psychotic Disorders (Schizoaffective Disorder)
01/2019 - 01/2019
2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
06/2014 - 08/2010
2Multiple Sclerosis
06/2014 - 08/2010
1Acute-Phase Reaction
03/2022
1Parasitic Diseases (Parasitic Disease)
05/2021
1Brain Injuries (Brain Injury)
01/2021
1Infections
01/2021
1Parkinson Disease (Parkinson's Disease)
01/2021
1Anemia
01/2018
1Cluster Headache (Cluster Headaches)
01/2015
1Headache Disorders (Headache Syndromes)
01/2015
1Spinocerebellar Ataxias (Spinocerebellar Ataxia)
11/2013
1Demyelinating Diseases (Demyelinating Disease)
08/2010
1Fatigue
04/2005
1Hyperlipidemias (Hyperlipidemia)
01/2004

Drug/Important Bio-Agent (IBA)

8KynurenineIBA
12/2020 - 06/2014
5Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
01/2018 - 10/2012
4cinnabarinic acidIBA
01/2022 - 06/2014
4Glutamic Acid (Glutamate)FDA Link
01/2019 - 08/2010
3Analgesics (Analgesic Drugs)IBA
01/2022 - 10/2012
3Proteins (Proteins, Gene)FDA Link
05/2021 - 11/2013
3Antipsychotic Agents (Antipsychotics)IBA
12/2020 - 12/2015
3xanthurenic acidIBA
01/2019 - 12/2015
3Tryptophan (L-Tryptophan)FDA Link
01/2017 - 04/2005
2LipidsIBA
06/2021 - 01/2004
2Phospholipids (Phosphatides)FDA LinkGeneric
06/2021 - 01/2004
2Triglycerides (Triacylglycerol)IBA
06/2021 - 01/2004
2Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2017
2Pharmaceutical PreparationsIBA
01/2019 - 12/2015
2N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
01/2015 - 01/2015
1LithiumIBA
10/2022
1Therapeutic UsesIBA
10/2022
1CadmiumIBA
05/2022
1AlbuminsIBA
03/2022
1Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
01/2022
1CholesterolIBA
06/2021
1metabotropic glutamate receptor 3 (mGluR3)IBA
01/2021
1Monoamine Oxidase (MAO)IBA
01/2021
1LigandsIBA
01/2019
1Endothelium-Dependent Relaxing Factors (Endothelium Derived Relaxing Factor)IBA
01/2017
1Memantine (Namenda)FDA Link
01/2015
1Glycine (Aminoacetic Acid)FDA LinkGeneric
01/2015
1Peptides (Polypeptides)IBA
06/2014
1Myelin-Oligodendrocyte GlycoproteinIBA
06/2014
1(3,4- dihydro- 2H- pyrano(2,3)b- quinolin- 7- yl)- (cis- 4- methoxycyclohexyl) methanoneIBA
11/2013
1Messenger RNA (mRNA)IBA
11/2013
1N- cyclobutyl- 6- ((3- fluorophenyl)ethynyl)nicotinamideIBA
11/2013
1Cysteine (L-Cysteine)FDA Link
10/2012
1Freund's AdjuvantIBA
10/2012
1LY 341495IBA
10/2012
1Acute-Phase Proteins (Acute-Phase Protein)IBA
11/2011
1metabotropic glutamate receptor 4IBA
08/2010
1Serotonin (5 Hydroxytryptamine)IBA
04/2005
1ChymotrypsinFDA Link
01/2004
1Nonesterified Fatty Acids (NEFA)IBA
01/2004

Therapy/Procedure

2Injections
01/2021 - 10/2012
1Protein-Restricted Diet (Diet, Protein Restricted)
01/2021
1Controlled Hypotension
01/2017
1Analgesia
10/2012